Metabolism of Aromatic Amino Acids in Microorganisms

Metabolism of aromatic amino acids and amines.

The metabolism of aromatic amino acids in leukemic rats.

Previous reports from this laboratory have shown that the concentrations of some of the circulating free amino acids in the plasma of leukemic patients were higher when compared with values obtained from normal individuals (6, 20). In particular, it was found that the leukemic patients exhibited abnormally elevated values for valine, phenylalanine, tyrosine, isoleucine, and glutamic acid. To in...

Pathways of biosynthesis of aromatic amino acids and vitamins and their control in microorganisms.

INTRODUCTION The aims ofthis review are to present an outline of the metabolic pathways leading to the aromatic amino acids and vitamins and to discuss how the flow of intermediates along these pathways is controlled. The general outlines of the pathways to the aromatic amino acids, phenylalanine, tyrosine, and tryptophan have been known for some time, and they were excellently reviewed by Umba...

4 Aromatic Amino Acids in the Brain

This chapter describes the aromatic L‐amino acids tryptophan and tyrosine and the effects on tyrosine metabolism of phenylalanine. Tryptophan and phenylalanine are essential amino acids and must ultimately be derived from dietary proteins; tyrosine is obtained both from dietary proteins and from the hydroxylation of phenylalanine by phenylalanine hydroxylase (PAH). The proportions of dietary tr...

The Metabolism of Amino Acids

It was shown by Seth and Luck (1) that the intestinal absorption of glycine and alanine by rabbits was followed by pronounced aminoacidemia. Other amino acids when administered in similar amounts provoked smaller increases in the amino nitrogen content of the blood. Glutamic acid and aspartic acid were absorbed with but a slight aminoacidemia. The question then arose as to whether these strikin...